A Clinical Trial of Ginseng in Diabetes

The Washington University

Status and phase: Completed; Early Phase 1

Conditions: Diabetes

Treatments: Drug: ginsenoside RE; Drug: Ginseng; Dietary Supplement: Placebo (sugar pill)

Study type: Interventional

Funder types: Other

Identifiers

NCT00781534

03-0824

Details and patient eligibility

About

a clinical study of Ginseng its potential affect on diabetes

Full description

Comparing three groups (those with & without normal blood sugar levels) to see if there is any clinically significant change in blood sugar levels in relationship to those taking:

1. ginseng
2. ginsenoside RE (a type of metabolized ginseng)
3. placebo

Enrollment: 19 patients

Sex: All

Ages: 18 to 65 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• ages 18-65
• healthy, non-diabetic
• healthy, impaired glucose tolerance/mild diabetes (no medications required)

Exclusion criteria

• impaired glucose tolerance (borderline diabetes that requires medications)
• diabetes (requiring medications)
• caffeine sensitivity
• known cardiac, peripheral vascular diseases
• arrhythmias (irregular heart rhythms)

Trial design

Primary purpose: Basic Science

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Quadruple Blind

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19 participants in 3 patient groups, including a placebo group

1. Ginseng

Active Comparator group

Description:

Ginseng group

Treatment:

Drug: Ginseng

Drug: Ginseng

2. Ginsenosdie RE

Active Comparator group

Description:

Ginsenoside RE (a metabolite of ginseng) group

Treatment:

Drug: Ginseng

Drug: ginsenoside RE

Drug: Ginseng

3. Placebo

Placebo Comparator group

Description:

placebo ("sugar" pill) group

Treatment:

Dietary Supplement: Placebo (sugar pill)