A Cognitive Training Tool Based on Life-logging in Mild Cognitive Impairment (ReMemory-MCI)

Consorci Sanitari de Terrassa

Status

Unknown

Conditions

Mild Cognitive Impairment

Treatments

Behavioral: Control intervention

Behavioral: ReMemory-MCI training

Study type

Interventional

Funder types

Other

Identifiers

NCT02592187

Fundacio la MaratóTV3 20141510

Details and patient eligibility

About

Background: Mild Cognitive Impairment (MCI) is a risk factor for dementia and represents a critical window of opportunity to intervene and alter the trajectory of both cognitive and functional decline. Emerging life-logging technologies has shown a tremendous potential to increase autobiographical memory.

Objective: The main goal of the present study is to develop a Cognitive Training program (CT) for MCI based on life-logging captured by a Wearable Camera (WeC) recording specific autobiographical episodes for stimulating posteriorly episodic memory. The challenge is to create an application to manage this large collection of images, which can be easily retrieved as events by users in a therapeutic context as a multimodal cognitive stimulation. The investigators will conduct a quasi-experimental design with non-equivalent control group, evaluating the effectiveness of the life-logging re-experiencing program immediately and 3-month follow-up period.

Methodology: The design is a pretest, posttest and follow-up design, where 30 adults with MCI were sequentially allocated to one of two conditions: intervention or control group. All subjects wore a lifelogging WeC during two weeks, and subsequently they were generated several videos with the most relevant information of each event. Subjects in the Intervention Group will attend 1-hour individual training sessions 2 times per week for 14 8 weeks. Main outcomes measures will be cognitive, functional, emotional and quality of life measures, as well as biochemical measures (BDNF).

Expected results: The investigators expect the outcomes to provide preliminary evidence that autobiographical experimentation CT programs can positively impact cognitive functioning and may represent an effective strategy to improve memory and functionality in those who begun to experience cognitive decline.

Enrollment

30 estimated patients

Sex

All

Ages

65 to 90 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

65-90 years of age
Meet definition criteria for MCI (Petersen, 2004)
Be receiving CT at least three month in Day Hospital during three months or more; c) having memory complaint, usually verified by an informant
Having memory complaint, usually verified by an informant
Memory performance below the mean score for the corresponding age and education group
Having normal general cognitive functioning as determined by a Mini-Mental State Examination (MMSE) score > o = 24
Having a reliable caregiver who can supervise the patient's daily activities
Having Global clinical dementia rating scale score of 0.5
Granted written informed consent accepting to participate in the study

Exclusion criteria

Neurological, psychiatric or unstable medical disorders
Intellectual deficiency (Premorbid Intellectual Quotient (IQ) -Vocabulary- less 85)
Relevant hearing, vision, motor or language deficits
Less than 4 years of education e) acquisition of Catalonian or Spanish languages after 15 years old