A Cohort Study on the Efficacy of Bariatric Surgery for Rapidly Progressing Diabetic Nephropathy (EBSDKD)

China-Japan Friendship Hospital

Status: Enrolling

Conditions: Diabetic Nephropathy; Bariatric Surgeries

Treatments: Other: Non-surgical therapy; Procedure: Bariatric surgery

Study type: Observational

Funder types: Other

Identifiers

NCT06661174

EBSDKD

Details and patient eligibility

About

Establish a cohort of diabetic kidney disease(DKD) patients with intensive weight loss treatment to evaluate the impact of intensive weight loss treatment on the renal prognosis of DKD and construct a prediction model for the improvement of renal outcomes after weight loss.

Enrollment: 100 estimated patients

Sex: All

Ages: 18 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age 18 to 65 years old;

  • BMI>25Kg/m2 or abdominal obesity (i.e. waist circumference>90cm for men and>85cm for women);

    • eGFR<30ml/min/1.73m2 or urinary microalbumin≥300mg/g, eGFR<60ml/min/1.73m2.

Exclusion criteria

• Patients who are taking glucocorticoids;

  • Combined with tumors; ③Combined with autoimmune diseases; ④Serum albumin<25g/L.

Trial design

100 participants in 2 patient groups

Surgical group

Treatment:

Procedure: Bariatric surgery

Other: Non-surgical therapy

Non-surgical group

Treatment:

Other: Non-surgical therapy