A Cohort Study on Thrombectomy for Stroke

Ning Wang, MD., PhD.

Status: Enrolling

Conditions: Ischemic Stroke

Study type: Observational

Funder types: Other

Identifiers

NCT04637074

MRCTA, ECFAH of FMU [2020]389

Details and patient eligibility

About

The cerebral collateral circulation refers to the subsidiary network of vascular channels that stabilize cerebral blood flow when principal conduits fail. Collateral status differs among patients with acute ischemic stroke. Relatively sparse attention has been devoted to the role of baseline collateral circulation in patients with acute ischemic stroke who are candidates for revascularization. This study aim to investigate the correlation between baseline collateral circulation and the likelihood of opening of an arterial occlusion, the extent of reperfusion, tissue injury and clinical impairment.

Enrollment: 300 estimated patients

Sex: All

Ages: 18 to 85 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age ≥ 18 years.
• Mechanical thrombectomy initiated within 24 hours after onset
• CT perfusion can be performed before the initiation of thrombectomy and 24h after thrombectomy

Exclusion criteria

• Contraindication to imaging with contrast agents
• Delay between imaging and beginning of thrombectomy > 90 minutes