A Community-based, Behavioral Intervention to Improve Screening for Hepatitis C Among High-risk Young Adults in Wisconsin (Hep-Net)

University of Wisconsin (UW)

Status: Completed

Conditions: Hepatitis C

Treatments: Behavioral: Hep-Net Intervention; Behavioral: Usual Care

Study type: Interventional

Funder types: Other

Identifiers

NCT02474043

2013-1360

Details and patient eligibility

About

The goal of this study is to evaluate the effectiveness of a brief, computerized behavioral intervention for promoting screening for hepatitis C and reducing risky behavior for people who inject drugs (PWID).

Full description

People who inject drugs (PWID) are at high risk for hepatitis C virus (HCV) infection if they share contaminated injection equipment with others. Many are infected but are unaware of it, making it likely they will transmit the virus to others if they share contaminated injecting equipment. Problems related to hepatitis C can be avoided if people know their status by getting tested and referred to treatment.

In this study, the investigators will recruit eligible PWID in several cities in Wisconsin using a social networks strategy, in which clients who receive services at a syringe exchange program are asked to refer peers who also inject drugs to participate in the study. All participants will undergo a baseline computerized risk assessment that elicits information about hepatitis C status, previous testing, transmission risk behaviors, and overdose risk. Participants will then be randomly-assigned to receive either standard risk reduction counseling from a prevention specialist, or computerized tailored risk reduction messages that are specific to their reported risk behaviors, attitudes and beliefs. A follow-up assessment will be completed after 3 months to evaluate changes in behavioral risk and intention to undergo HCV screening. A database will be searched to determine which participants returned for HCV screening within 12 months of enrollment, and of those, which ones tested positive for HCV.

Enrollment: 235 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age 18 or over
• English-speaking
• Reports injection of illicit drugs in the past month

Exclusion criteria

• Unable to provide informed consent due to cognitive impairment
• Unwilling to provide personal locator information and consent to be contacted for follow-up after 3 months.
• Currently known to be pregnant

Trial design

Primary purpose: Screening

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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235 participants in 2 patient groups

Usual care

Active Comparator group

Description:

Standard health education and prevention counseling by trained staff

Treatment:

Behavioral: Usual Care

Hep-Net Intervention

Experimental group

Description:

Computerized tailored behavioral intervention

Treatment:

Behavioral: Usual Care

Behavioral: Hep-Net Intervention