A Comparative Analysis of Intertransverse Nerve Block and Paravertebral Nerve Block in Endoscopic Hepatectomy

Jie Chen

Status: Active, not recruiting

Conditions: Pain

Treatments: Other: Nerve block

Study type: Interventional

Funder types: Other

Identifiers

NCT06553495

2024-098

Details and patient eligibility

About

This study aims to compare the analgesic effect of intertransverse nerve block and paravertebral nerve block after endoscopic hepatectomy, evaluate its effectiveness and safety, and provide new ideas and clinical basis for postoperative pain management of liver surgery.

Full description

This study was a prospective, double-blind, randomized controlled trial. Patients who were eligible for laparoscopic partial liver resection in our center were included, with intertransverse nerve block as the experimental group and paravertebral nerve block as the control group. Through the analysis of postoperative pain score 30min to 24h, the number of effective analgesic pump compressions within 24h, the amount of analgesic drugs used, complications and other data, To evaluate the efficacy and safety of intertransverse nerve block in patients undergoing laparoscopic partial liver resection.

Enrollment: 80 estimated patients

Sex: All

Ages: 18 to 80 years old

Volunteers: Accepts Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria:1:

1.18-80 years old adult, BMI<27.9kg/m2

2: 2. American Society of Anesthesiologists ASA Grade I-III

3: 3. Patients with laparoscopic partial liver resection such as liver tumors

4: 4. Willing to participate in this study and sign the informed consent form

Exclusion Criteria:

1. 1. The patient or family member refuses to sign the informed consent form
2. 2. Blood coagulation dysfunction, local infection
3. 3. Those who have communication, communication disorders or mental abnormalities
4. 4. Patients with severe heart, pulmonary and renal insufficiency or patients with central system diseases

5. 5. For any reason, it cannot be matched with the study or the researcher believes that it is not appropriate to be included in this experiment.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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80 participants in 2 patient groups, including a placebo group

intertransverse nerve block

Experimental group

Description:

To study the analgesic effect of intertransverse nerve block after endoscopic hepatectomy

Treatment:

Other: Nerve block

paravertebral nerve block

Placebo Comparator group

Description:

To study the analgesic effect of paravertebral nerve block after endoscopic hepatectomy

Treatment:

Other: Nerve block