"A Comparative Clinical Evaluation of the Efficacy of Topical Adapalene, Benzoyl Peroxide Gel, Oral Lactobacillus Rhamnosus, D-chiro-inositol, Inulin Capsule, and Their Fixed Combination in Mild to Moderate Acne Vulgaris Patients."

Treatment and Diagnostic Center of Private Enterprise "Asklepiy"

Status: Active, not recruiting

Conditions: Acne Vulgaris

Treatments: Dietary Supplement: Oral Lactobacillus Rhamnosus, D-chiro-inositol, Inulin Capsule; Drug: Topical Adapalene, Benzoyl Peroxide Gel

Study type: Interventional

Funder types: Other

Identifiers

NCT05855629

EDA1370

Details and patient eligibility

About

The study aims to conduct a comparative clinical evaluation of the effectiveness of a fixed topical combination of adapalene with benzoyl peroxide in the form of a gel, a fixed combination of Lactobacillus rhamnosus, D-chiro-inositol and inulin in the form of capsules and their combination in patients with acne vulgaris of mild and moderate severity and laboratory lipid analysis profile of sebum, lipid metabolism, and IGF-1 (insulin-like growth factor).

Enrollment: 59 patients

Sex: All

Ages: 18 to 27 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Patients with mild to moderate level of Acne Vulgaris

Exclusion criteria

• Pregnancy

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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59 participants in 3 patient groups

Topical Adapalene, Benzoyl Peroxide Gel

Other group

Treatment:

Drug: Topical Adapalene, Benzoyl Peroxide Gel

Oral Lactobacillus Rhamnosus, D-chiro-inositol, Inulin Capsule

Other group

Treatment:

Dietary Supplement: Oral Lactobacillus Rhamnosus, D-chiro-inositol, Inulin Capsule

Topical Adapalene,Benzoyl Peroxide Gel,Oral Lactobacillus Rhamnosus,D-chiro-inositol,Inulin Capsule

Other group

Treatment:

Drug: Topical Adapalene, Benzoyl Peroxide Gel

Dietary Supplement: Oral Lactobacillus Rhamnosus, D-chiro-inositol, Inulin Capsule