ClinicalTrials.Veeva

Menu

A Comparative Clinical Study to Evaluate Crowns Designed by Artificial Intelligence Versus Crowns Designed Traditional Design Software (AI)

T

Tishreen University

Status

Not yet enrolling

Conditions

Dental Crown

Treatments

Other: Crowns

Study type

Interventional

Funder types

Other

Identifiers

NCT07099261
Tishreen U ـProsthodontics

Details and patient eligibility

About

This clinical research aims to Evaluate Crowns Designed by Artificial Intelligence Versus Crowns Designed by Traditional Design Software

The research will be conducted on a sample of patients with an indication for crowning of the first lower molar. Ten dental crowns will be prepared.

After obtaining written consent from patients who meet the inclusion and exclusion criteria, 10 dental crowns will be prepared. Measurements will be taken using silicone impressions and then converted into digital format.

The digital impression will be sent to the selected dental restoration design software used in the study. The same parameters will be adjusted in all software programs for each crown.

After the design is completed, the designs will be sent to the milling unit. For each case, three crowns will be designed and milled from polymethyl methacrylate (PMMA).

The crown will be clinically examined and evaluated according to specific criteria. Marginal fit, proximal contact quality, and occlusion will be assessed.

The best crown will be milled from zirconia and delivered to the patient.

Full description

Recent advancements in artificial intelligence (AI) have revolutionized various fields, including dentistry, where AI systems are being promoted to reduce design time for dental restorations. However, it remains unclear whether this increased speed compromises critical factors such as marginal fit accuracy, occlusion, and contact points-elements crucial for the success of dental prosthetics. The existing scientific evidence regarding the efficiency of AI-supported dental design systems is limited. A review of the literature revealed only one clinical study addressing this aspect, highlighting the urgent need for further comparative research.

This clinical research aims to Evaluate Crowns Designed by two Artificial Intelligence computer-aided AIـCAD Versus Crowns Designed by Traditional Design Software One Traditional CAD by assessing the following metrics:

  1. Marginal fit accuracy
  2. Quality of contact points
  3. Occlusion

Importance of the Research

Given the scarcity of studies focusing on AI-based crown design systems clinically, this research will assist dental clinics and laboratories in making informed decisions regarding the adoption of AI technologies versus continuing with traditional methodologies.

Study Design

self controlled clinical trial

Clinical Procedures

  1. Tooth Preparation: Prepare the teeth to receive a zirconia crown.
  2. Impression Taking: Obtain impressions using silicone.
  3. Digital Conversion: Convert impressions into a digital model using a laboratory scanner.
  4. Designing : Send the digital model to selected crown design programs (both AI-driven and traditional).
  5. Crown Fabrication: After design approval, crowns will be produced from PMMA using a milling unit.
  6. Clinical Evaluation: Conduct a clinical assessment of the crowns. Evaluation Metrics

Marginal Fit Accuracy

Measurement clinically using a probe. Comparison with silicone replica technique or Analysis through 3D modeling software (X control GEOM).

Contact Points Quality

Measure the force required to pull a dental floss between teeth.

Occlusion Assessment

Utilize 100-micron and 12-micron articulating paper and Shimstock to evaluate occlusal contact points.

Data will be analyzed using appropriate statistical methods to compare the outcomes between AI-driven designs and traditional methods, ensuring robust conclusions regarding their efficacy.

The results of this study are anticipated to provide valuable insights into the reliability and quality of AI-based crown design systems compared to traditional methods, guiding dental practices in their decision-making processes regarding technology adoption.

This proposal serves as a foundation for conducting a thorough investigation into the effectiveness of AI in dental crown design, addressing a critical gap in current research and practice

Enrollment

10 estimated patients

Sex

All

Ages

18 to 60 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  • Patients aged 18-60 years requiring a crown for a lower first molar
  • Good oral and gingival health
  • adjacent teeth in good condition
  • Natural opposing teeth
  • Willingness to participate and sign informed consent

Exclusion criteria

  • Abnormal occlusal habits such as bruxism
  • Active periodontal diseases
  • Allergy to crown materials (e.g., polymethyl methacrylate, PMMA)
  • Poor oral hygiene

Trial design

Primary purpose

Treatment

Allocation

Non-Randomized

Interventional model

Single Group Assignment

Masking

Single Blind

10 participants in 3 patient groups

Crowns designed with AI powered dentibird
Experimental group
Description:
10 Crowns designed with AI powered dentbird
Treatment:
Other: Crowns
Crowns designed with AI powered Exocad
Experimental group
Description:
10 Crowns designed with AI powered Exocad
Treatment:
Other: Crowns
Crowns designed with conventional Exocad
Sham Comparator group
Description:
10 Crowns designed with conventional Exocad (computer aided experienced)
Treatment:
Other: Crowns

Trial contacts and locations

0

Loading...

Central trial contact

Rima Saker, Assistant professor; Zeyad Handhal, master's student

Data sourced from clinicaltrials.gov

Clinical trials

Find clinical trialsTrials by location
© Copyright 2026 Veeva Systems