A Comparative Study of Depth of Anesthesia Monitored by Bispectral Index (BIS) Values

Shiraz University of Medical Sciences

Status and phase: Completed; Phase 2

Conditions: Anesthetics

Treatments: Drug: thiopental,propofol; Drug: propofol

Study type: Interventional

Funder types: Other

Identifiers

NCT01140100

85-3211

Details and patient eligibility

About

The aim of this study is to determine whether induction of anesthesia with thiopental followed by propofol infusion is able to maintain sufficient depth of anesthesia .

Enrollment: 82 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• being adult
• having ASA I or II
• scheduled for elective cataract surgery under general anesthesia

Exclusion criteria

• massive obesity
• intake of any central nervous system (CNS) stimulants
• intake of CNS depressants
• intake of Tricyclic antidepressants
• known adverse reaction to the study drugs

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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82 participants in 2 patient groups

propofol-propofol

Active Comparator group

Treatment:

Drug: propofol

thiopental-propofol

Experimental group

Treatment:

Drug: thiopental,propofol