A Comparative Study of the Efficacy of Transcatheter Arterial Chemoembolization (TACE) and Transcatheter Arterial Pegylated Interferon Embolization (TAIE) for Liver Cancer

Hospital Authority, Hong Kong

Status: Unknown

Conditions: Carcinoma, Hepatocellular

Treatments: Procedure: Transcatheter Arterial Chemoembolization (TACE); Procedure: Transcatheter Arterial Pegylated Interferon Embolization (TAIE)

Study type: Interventional

Funder types: Other; Industry

Identifiers

NCT00563095

EC 1942-02

HARECCTR0500039

Details and patient eligibility

About

Primary: To compare the efficacy of TACE and TAIE.

Secondary: To compare the side effects of TACE and TAIE.

The outcome measurements include survival benefit and tumour regression induced by the two therapies.

Enrollment: 100 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Confirmed hepatocellular carcinoma not suitable for surgery

Exclusion criteria

• Portal vein thrombosis
• Severe arteriovenous shunt
• Bilirubin level > 50 umol/mL
• Prothrombin time > 5 seconds

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)