A Comparative Study of Two Patterns of Controlled Ovarian Hyperstimulation in Mid Follicular Phase or Early Luteal Phase for Egg Donors

Parc de Salut Mar

Status: Completed

Conditions: Stimulation in the Ovary

Treatments: Procedure: Early luteal phase; Procedure: Late follicular phase -COH-

Study type: Interventional

Funder types: Other

Identifiers

NCT01385332

UREP-ONCO-2010

Details and patient eligibility

About

The purpose of this study is to determine the efficacy and safety of two new patterns of controlled ovarian hyperstimulation (defined as total number of picked up eggs). This study will be performed in egg donors but these new patterns will be implemented in fertility preservation patients.

Enrollment: 10 patients

Sex: Female

Ages: 18 to 30 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• premenopausal women 18-30 years old, with FSH levels < 10mIU
• irregular menstrual cycle
• BMI between 12-28
• signed inform consent

Exclusion criteria

• Polycystic ovarian syndrome, gonadotropins allergy

Trial design

Primary purpose: Treatment

Allocation: Non-Randomized

Interventional model: Crossover Assignment

Masking: None (Open label)

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10 participants in 2 patient groups

Early luteal phase -COH-

Active Comparator group

Description:

We perform an standard antagonist protocol beginning the second day of the menstrual cycle compared with an antagonist protocol beginning in the early luteal phase.

Treatment:

Procedure: Early luteal phase

Late folicular phase - COH -

Active Comparator group

Description:

We perform an standard antagonist protocol beginning the second day of the menstrual cycle compared with an antagonist protocol beginning in the late follicular phase.

Treatment:

Procedure: Late follicular phase -COH-