A Comparative Study on the Efficacy of Blue Light Emitting Diodes Therapy Versus Targeted Narrow Band UVB in Stable Non-segmental Vitiligo Patients. (Nb-UVB)

Cairo University (CU)

Status and phase: Completed; Phase 4

Conditions: Vitiligo

Treatments: Device: Narrow Band UVB Treatment; Device: blue light emitting diode

Study type: Interventional

Funder types: Other

Identifiers

NCT07174024

MS-92-2025

Details and patient eligibility

About

A comparative study on the efficacy of blue light emitting diodes therapy versus targeted Narrow band UVB in stable non-segmental vitiligo patients.

Full description

A comparative study on the efficacy of blue light emitting diodes therapy versus targeted Narrow band UVB in stable non-segmental vitiligo patients.

Enrollment: 30 patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• All age group.

  • Both genders.
  • Subjects with stable non-segmental vitiligo (≥2 patches) acral or non-acral patches of diameter ≤ 2cm.

Exclusion criteria

• Prior treatment with laser therapies for at least 3 months

  • Recent exfoliation procedures.
  • Recent surgical procedures.
  • Poor skin conditions including keloids.
  • Hypersensitivity to light ( visible and near-infrared).
  • Medications that make users more sensitive to light.
  • Anticoagulant and immunosuppressive treatments.
  • Gestations or breastfeeding.
  • A personal or family history of skin cancer.
  • Unstable vitiligo (older lesions have not progressed for the last 1 years and lack of Koebner phenomena ).

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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30 participants in 2 patient groups

patients will receive NB-UVB phototherapy sessions on a Randomly selected patch

Active Comparator group

Description:

patients will receive NB-UVB phototherapy sessions on a Randomly selected patch

Treatment:

Device: Narrow Band UVB Treatment

Patients will receive blue light emitting diodes phototherapy on a randomly selected patch

Active Comparator group

Description:

Patients will receive blue light emitting diodes phototherapy on a randomly selected patch

Treatment:

Device: blue light emitting diode