A Comparison Between Neurostimulation and Loss of Resistance for Cervical Paravertebral Blocks

McGill University

Status: Unknown

Conditions: Shoulder Surgery

Treatments: Other: Nerve stimulation; Other: Loss of resistance to air

Study type: Interventional

Funder types: Other

Identifiers

NCT00640380

GEN-07-052

Details and patient eligibility

About

Cervical paravertebral blocks (CPVBs) target the brachial plexus from a puncture site situated in the posterior aspect of the neck and represent an alternative to interscalene blocks (ISBs) for shoulder and proximal humeral surgery. Randomized controlled trials comparing CPVB and ISB have found no significant differences in success rate, onset and offset times. Because of the reliability of their cutaneous landmarks, CPVBs have become part of the investigators' standard practice. With this approach, the brachial approach can be identified either with loss of resistance to air (LOR) or nerve stimulation (NS). While some authors have used only LOR and reported good success rates, others have hypothesized that NS may increase the reliability of the block. In the proposed study, for the first time, the 2 methods will be formally compared.

Enrollment: 90 estimated patients

Sex: All

Ages: 18 to 70 years old

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria are:

• age between 18 and 70 years
• American Society of Anesthesiologists classification 1-3
• body mass index between 20 and 28

Exclusion criteria are:

• adults who are unable to give their own consent
• pre-existing obstructive or restrictive lung disease (assessed by history and physical examination)
• pre-existing neuropathy (assessed by history and physical examination)
• coagulopathy (assessed by history and physical examination and, if deemed clinically necessary, by blood work up ie platelets≤ 100, International Normalized Ratio≥ 1.4 or prothrombin time ≥ 50)
• renal failure (assessed by history and physical examination and, if deemed clinically necessary, by blood work up ie creatinine≥ 100)
• hepatic failure (assessed by history and physical examination and, if deemed clinically necessary, by blood work up ie transaminases≥ 100)
• allergy to local anesthetic agents (LA)
• pregnancy
• prior cervical spine surgery

Trial design

90 participants in 2 patient groups

1

Experimental group

Description:

CPVB with NS

Treatment:

Other: Nerve stimulation

2

Active Comparator group

Description:

CPVB with LOR

Treatment:

Other: Loss of resistance to air