A Comparison Between Sonoguided Injection Corticosteroid and Hyaluronic Acid Injection in Treatment of Trigger Finger

Taipei Veterans General Hospital

Status: Completed

Conditions: Trigger Finger

Treatments: Drug: triamcinolone acetonide; Drug: Hyaluronic Acid

Study type: Interventional

Funder types: Other

Identifiers

NCT01950793

2012-11-001A

Details and patient eligibility

About

The study is to compare the effect between steroid injection and Hyaluronic acid in treatment trigger finger. Using sonoguided injection technique achieves more accurate injection location and therapeutic effect. We hypothesize hyaluronic acid has both lubricant and anti-inflammation effect in treatment of trigger finger, and can provide better outcome and lower adverse effect than steroid injection.

Full description

This is a prospective, randomized, double-blinded controlled study. Patients with the diagnosis of trigger finger will be recruited and enrolled from Taipei Veteran General Hospital PM&R outpatient clinic. Subjects will be randomized into two groups; hyaluronic acid and triamcinolone acetonide injections, both via ultrasound-guided with one injection only.We hypothesize that through the anti-inflammatory property of the hyaluronate acid, the treatment effects will be as effective as the traditionally used steroid injections with equal or even lower recurrence rate for treatment of trigger finger. We expect that injections of hyaluronate into tendon sheath could become a new treatment option for trigger finger.

Enrollment: 36 patients

Sex: All

Ages: 20 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• patients with trigger digits and patients
• without previous treatment of the trigger digit

Exclusion criteria

• patients with prior treatment of the trigger digit (eg, splinting, injection, or therapy),
• patients less than
• 20 years old,
• patients with allergy or contraindication to hyaluronic acid,
• patients with trigger digits due to rheumatoid arthritis,
• and patients with infection at the site of injection.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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36 participants in 2 patient groups

steroid

Active Comparator group

Description:

used ultrasound-guided inject 1c.c triamcinolone acetonide 10mg/mL (Shincort®, YSP, Taiwan)into the sheath of the flexor tendons, penetrated to the A1 pulley. One injection only

Treatment:

Drug: triamcinolone acetonide

Hyaluronic acid

Experimental group

Description:

used ultrasound-guided inject 1c.c Hyaluronic acid (Artz®, Seikagaku, Japan)into the sheath of the flexor tendons, penetrated to the A1 pulley. One injection only

Treatment:

Drug: Hyaluronic Acid