A Comparison Between The Efficacy of Modified Thoracoabdominal Plane Block Via Perichondral Approach (M-TAPA) And External Oblique Intercostal Plane Block (EOIPB) in Patients Undergoing Laparoscopic Cholecystectomy Surgeries (LC)

Kasr El Aini Hospital

Status: Not yet enrolling

Conditions: Post Operative Pain

Treatments: Procedure: Bilateral Ultrasound Guidance EOIPB; Other: Bilateral Ultrasound Guidance M-TAPA

Study type: Interventional

Funder types: Other

Identifiers

NCT06810206

MD-462-2024

Details and patient eligibility

About

Because laparoscopic procedures have a number of benefits over open procedures, they have completely changed the surgical industry.(1) Laparoscopic cholecystectomy (LC) is a minimally invasive technique that usually yields less discomfort following surgery, shorter hospital stays, and quicker patient recovery, plus it's an economical operation. Nevertheless, it results in moderate to severe pain.(2).By using regional anesthesia techniques to effectively control pain and lessen the requirement for opioid analgesics, ERAS implementation has demonstrated significant decreases in opioid usage and improved overall patient outcomes (3). (4) To minimize the need for opioids, opioid sparing anesthesia employs a multimodal strategy that includes nonsteroidal anti-inflammatory medications, paracetamol, local anesthetics (LA), and, if feasible, regional anesthetic techniques and regional analgesia. (5) With fewer systemic side effects, regional anesthetic techniques-like nerve blocks-offer tailored pain treatment. The best regional pain management strategy for LC surgery is still unknown, though.(4) Modified Thoracoabdominal Nerves Block Through Perichondral Approach (M-TAPA) Block is a new technique defined as a modification of TAPA Block in which local anaesthetics are administered only to the underside of the perichondral surface, creating a sensory block between T5-T12 dermatomes. While the external oblique intercostal plane (EOIPB) block provides blockade of the lateral and anterior cutaneous branches of the intercostal nerves from T6/7 to T10/11.This study aims to compare the efficacy of both MTAPA and EOIPB in patients undergoing LC surgery .

Enrollment: 60 estimated patients

Sex: All

Ages: 18 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Adults aged 18-65 years
• Scheduled for Laparoscopic cholecystectomy surgery
• ASA (American Society of Anaesthesiologists) physical status I-II

Exclusion criteria

• Known allergy to local anaesthetics
• Coagulopathy or anticoagulant use
• Infection at the site of block
• Chronic pain conditions
• Advanced liver or kidney failure
• History of abdominal surgery or trauma
• Alcohol or drug use
• Refusal to participate
• Chronic opioid consumption
• Use of painkillers in the preoperative 24hours
• Conversion to open surgery
• Body mass index ( BMI ) > 35

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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60 participants in 2 patient groups

Group A

Active Comparator group

Description:

Group A: 30 patients will receive the MTAPA.

Treatment:

Other: Bilateral Ultrasound Guidance M-TAPA

Group B

Active Comparator group

Description:

Group B: 30 patients will receive the EOIPB.

Treatment:

Procedure: Bilateral Ultrasound Guidance EOIPB