A Comparison Between Two Types of Sealers in the Healing of Periapical Lesions

Damascus University

Status: Completed

Conditions: Periapical Lesions

Treatments: Procedure: Root canal treatment with AH Plus sealer; Procedure: Root canal treatment with BioCeramic sealer

Study type: Interventional

Funder types: Other

Identifiers

NCT06400030

UDDS-Endo-1-2024

Details and patient eligibility

About

This clinical study will evaluate the effect of BioCeramic sealer with single cone compared with the control group treated with AH Plus with lateral condensation in root canal obturation on the healing of periapical lesions.

The study sample will consist of 41 patients with 65 teeth with clear periapical lesions.

Root canal obturation will be applied for all patients. BioCeramic sealer will be applied for the experimental group only.

The changes of the dimensions of the periapical lesion will be assessed using CBCT radiographs; pre- and post- treatment changes for each group will be evaluated individually.

Full description

Periapical lesions is considered as the most common symptoms associated with infected root canals.

Recently, the BioCeramic sealer has been considered one of the most common endodontic sealer that possess antibacterial properties, so it can have an effective role in the healing of periapical lesions, as well as its ability to prevent periapical leakage due to its attachment to the dentinal walls and gutta-percha cones.

This study will evaluate the effect of BioCeramic sealer on the healing of periapical lesions and the changes of the dimensions of the lesions.

Root canal obturation with gutta-percha cones will be applied in the two groups: The control group will receive the AH Plus with lateral condensation technique, and the experimental group will receive BioCeramic sealer with single cone technique.

CBCT radiographs will be gotten before and after one year of the treatment to evaluate the periapical lesion dimensions changes.

Enrollment: 41 patients

Sex: All

Ages: 18 to 45 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• One maxillary anterior tooth with a clear periapical lesion at least.
• Normal anatomic features and straight or slightly curved roots.
• The treated teeth must have complete roots and a closed apex.
• The ability to isolate the teeth with a rubber dam and restore them.
• Good oral hygiene.
• Good systemic health.

Exclusion criteria

• Root caries.
• Root fractures or resorption.
• Signs of occlusal trauma on the treated tooth.
• Internal or external resorption.
• Active periodontal disease.
• Pregnancy or lactation.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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41 participants in 2 patient groups

AH Plus sealer Group (Control Group)

Other group

Description:

in this group, root canal system was filled with AH Plus sealer in conjunction with lateral condensation.

Treatment:

Procedure: Root canal treatment with AH Plus sealer

BioCeramic Sealer Group (Experimental Group

Experimental group

Description:

in this group, root canal system was filled with BioCeramic-based sealer in conjunction with single gutta-percha cone.

Treatment:

Procedure: Root canal treatment with BioCeramic sealer