A Comparison of Capsules and Oral Spray Solution as Methods of Delivering Vitamin D3 and Raising Status (SCD3)

Ulster University

Status: Completed

Conditions: Vitamin D Status; Vitamin D Concentration

Treatments: Dietary Supplement: 3000IU(75μg) vitamin D3

Study type: Interventional

Funder types: Other

Identifiers

NCT02608164

REC/15/0083

Details and patient eligibility

About

The aim of the study is to compare the effectiveness of a vitamin D3 oral spray solution with capsules at raising vitamin D status over winter.

This randomised crossover trial will aim to recruit a total of 22 healthy participants for a total of two 4-week interventions separated by a 10-week washout.

Enrollment: 22 patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Apparently healthy
• Over the age of 18

Exclusion criteria

• Those that intend to consume a supplement containing vitamin D at any point during the study
• Those under the age of 18.
• Individuals that are on prescribed medication that is known to affect vitamin D metabolism
• Those following a vegan diet
• Sun-bed users
• Participants that are planning a sun holiday during the study

Trial design

Primary purpose: Basic Science

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: None (Open label)

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22 participants in 2 patient groups

Vitamin D oral spray solution

Active Comparator group

Description:

An oral spray solution containing 3000IU (75micrograms) vitamin D3 per spray

Treatment:

Dietary Supplement: 3000IU(75μg) vitamin D3

Vitamin D capsules

Active Comparator group

Description:

A capsule containing 3000IU (75micrograms) vitamin D3 per capsule

Treatment:

Dietary Supplement: 3000IU(75μg) vitamin D3