A Comparison of Cognitive Processing Therapy (CPT) Versus Present Centered Therapy (PCT) for Veterans

VA Office of Research and Development

Status: Completed

Conditions: PTSD

Treatments: Behavioral: Cognitive Processing Therapy; Behavioral: Present Centered Therapy

Study type: Interventional

Funder types: Other U.S. Federal agency

Identifiers

NCT00607815

MHBA-007-07F

Details and patient eligibility

About

The purpose of this study is to compare the effectiveness of Cognitive Processing Therapy (CPT) versus Present Centered Therapy (PCT) for male OEF/OIF Veterans with combat related PTSD.

Full description

The purpose of this study is to compare the effectiveness of Cognitive Processing Therapy (CPT) versus Present Centered Therapy (PCT) for male OEF/OIF Veterans with combat related PTSD.

CPT has been shown to be effective in treating trauma survivors in several treatment outcome studies, but utility with Veterans has only been examined with male Veterans in one small pilot study. In addition CPT has never been compared to a treatment as usual or supportive psychotherapy condition to control for the specific and nonspecific elements of treatment. Although Cognitive Processing Therapy is one of the main treatment modalities at several VA's, including Cincinnati, it has never been compared to PCT, nor has it been used in a large, randomized study of male OEF/OIF Veterans. It is hypothesized that individual receiving CPT will show a larger reduction in posttraumatic stress disorder and related symptoms than those individuals receiving PCT.

All male OEF/OIF Veterans will be screened for their appropriateness for the study by phone screen and then by an assessment technician. The Veteran will be assessed at pre, post, 3-month, and 1-year follow-up. The assessment technicians will be blind to the participant's condition. CPT is a 12 week long individual psychotherapy treatment shown to be effective at reducing PTSD and related symptoms for survivors of various types of traumas, including combat. PCT is a supportive counseling treatment that has been utilized as an alternative to waitlist control in VA cooperative studies of PTSD.

Enrollment: 79 patients

Sex: Male

Ages: 18 to 75 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• PTSD;
• memory of the trauma;
• able to read/write;
• must be stable on medication for 3 months

Exclusion criteria

• Psychosis;
• suicidal/homicidal intent;
• alcohol/substance dependence;
• no memory of the trauma

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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79 participants in 2 patient groups

Cognitive Processing Therapy

Active Comparator group

Description:

Cognitive Processing Therapy

Treatment:

Behavioral: Cognitive Processing Therapy

Present Centered Therapy

Active Comparator group

Description:

Present Centered Therapy

Treatment:

Behavioral: Present Centered Therapy