A Comparison of Cognitive Training Approaches in Psychotic Disorders

Queen's University

Status: Completed

Conditions: Psychotic Disorders

Treatments: Behavioral: Cognitive Remediation - Perceptual Training; Behavioral: Cognitive Remediation - Executive Training

Study type: Interventional

Funder types: Other

Identifiers

NCT03024203

PSYC-173-16

Details and patient eligibility

About

Cognitive remediation (CR) is the best treatment to improve neurocognitive abilities for individuals with psychosis, however, there is no gold standard method of cognitive remediation available. Cognitive training refers to the training component of CR in which people practice computerized exercises that train specific cognitive abilities. There is no agreed upon approach within the field as to the type of training that is most effective with some studies, training higher level cognitive abilities, some training perceptual abilities, and others training general cognitive skills. This study will directly compare two competing methods of cognitive training on measures of neurophysiology, neurocognition, functional competence, and real-world functional performance.

Enrollment: 70 patients

Sex: All

Ages: 18 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• psychotic disorder
• No previous cognitive remediation in past 6 months

Exclusion criteria

• Brain injury
• Substance abuse
• Neurocognitive disorder
• Developmental Disability

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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70 participants in 2 patient groups

Executive Training

Experimental group

Description:

Executive Training (ET) involves training on computerized cognitive exercises that have graded increases in difficulty so that the participant is always challenged. A therapist will be in the room with participants to address any difficulties with the program and facilitate generation of strategies. ET will be delivered in both individual and group settings.

Treatment:

Behavioral: Cognitive Remediation - Executive Training

Perceptual Training

Experimental group

Description:

Perceptual Training (PT) involves training on computerized cognitive exercises that have graded increases in difficulty so that the participant is always challenged. A therapist will be in the room with participants to address any difficulties with the program and facilitate generation of strategies. PT will be delivered in both individual and group settings.

Treatment:

Behavioral: Cognitive Remediation - Perceptual Training