A Comparison of Colonic Bile Acid Content Following Right and Left Colectomies

Clalit Health Services

Status: Unknown

Conditions: Bile Acid and Salts; Colectomy

Study type: Observational

Funder types: Other

Identifiers

NCT02596516

MMC-0249-15

Details and patient eligibility

About

The aim of this study is to evaluate whether there is a difference in the bile acid content in the bowel in patients after right versus left colectomy. There is compelling evidence that patients under going resection of the right colon versus left coolon have a lower polyp detection rate in surveillance colonoscopies. The investigators intend to evaluate feces of patients undergoing left and right colectomies; prior to their surgery and again three and six months aftet the surgery. The investigators plan to compare the content of the different bile acids and to compare the content between the two groups.

Enrollment: 100 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Age above 18.
• Patients intended to undergo a colectomy for colonic cancer
• Patients willing and participate and able to sign an informed consent

Exclusion criteria

• Age under 18.
• Patients with Inflammatory Bowel Disease (Crohn's, Ulcerative colitis).
• Patients refusing to participate or are unable to understand or sign an informed consent