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A Comparison of Left and Right Radial Approach for Percutaneous Coronary Procedures

C

Capital Medical University

Status

Completed

Conditions

Transradial Approach,
Percutaneous Coronary
Coronary Angiography,

Treatments

Procedure: Right radial approach
Procedure: left radial approach

Study type

Interventional

Funder types

Other

Identifiers

Details and patient eligibility

About

Previous studies have shown that the transradial cardiac catheterization has decreased not only bleeding complications related to the access site and procedural discomfort but also morbidity and hospitalization as compared to transfemoral approach. At present, the right radial approach (RRA) is the first choice routinely for coronary angiography and interventions in daily clinical practice despite more marked subclavian artery tortuosity than left radial approach (LRA). Although LRA has been thought to be more direct access to the ascending aorta similar to transfemoral approach and may reduce fluoroscopy time and cerebrovascular complications compared with RRA, the application of LRA for coronary intervention is still low. Moreover, several studies have also obtained conflicting results showing no difference in procedural success rate compared LRA and RRA using Judkins catheters. To date, it remains unclear whether LRA is superior to RRA in term of safety and feasibility for coronary angiography and interventions in real world practice and few data of randomized control trial are available.

The aim of this study was to randomly investigate and compare the safety and feasibility of LRA compared with RRA for coronary diagnostic angiography in Chinese subjects.

The investigators will enroll consecutively for 2 years all patients undergoing coronary diagnostic procedures through trans radial approach.

The primary outcome was total procedural duration. Secondary outcomes included fluoroscopy time, dose of radiation including cumulative air kerma and dose area product, contrast volume and the incidence of vascular complications.

Enrollment

1,400 patients

Sex

All

Ages

20 to 85 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • All consecutive patients who undergo to diagnostic coronary procedures

Exclusion criteria

  • Acute ST-elevation myocardial infarction
  • Previous coronary artery bypass graft surgery
  • Hemodynamic instability

Trial design

Primary purpose

Treatment

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

None (Open label)

1,400 participants in 2 patient groups

Right radial approach
Experimental group
Description:
Coronary diagnostic procedures performed through right radial approach
Treatment:
Procedure: Right radial approach
Left radial approach
Experimental group
Description:
Coronary diagnostic procedures performed through left radial approach
Treatment:
Procedure: left radial approach

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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