A Comparison Of Local Anesthetic Agents And Steroid On Tracheal Tube Cuff (LA-STEROID)

Derince Training and Research Hospital

Status: Completed

Conditions: Anesthesia Intubation Complication; Sore Throat; Intubation Complication

Treatments: Drug: Mometasone nasal spray; Drug: Lidocaine 10% Spray

Study type: Interventional

Funder types: Other

Identifiers

NCT04085744

AOLC-1

Details and patient eligibility

About

This study aims to compare effects of two different agents on complications due to tracheal tube cuff in pediatric patients. Sore throat, hoarseness, laryngospasm, bronchospasm are the main complications.

Full description

In the literature there were studies about both local anesthetic agents and topical steroids and different densities of saline which were applied to decrease airway complications. In this study researchers intended to compare effects of local anesthetic agents and topical steroids applying around tracheal tube on airway complications which may occur in the first 24 hours after surgery. All pediatric patients scheduled for elective surgery will be recruited. enrolled patients will randomly assigned in to three groups: Control group, local anesthetic group and topical steroid group.

Enrollment: 91 patients

Sex: All

Ages: 2 to 18 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Being ages between 2 and 18
• undergoing elective surgery
• intubated patients over 1 hour
• ASA(American Society of Anesthesiologists) Class I-II patients

Exclusion criteria

• Urgent surgeries
• Tonsillectomies, adenoidectomies ..etc, operations that causes sore throat due to the operation area.

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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91 participants in 3 patient groups

control group

No Intervention group

Description:

In this group any drug will be applied on the cuff of the intubation tube

lidocaine group

Active Comparator group

Description:

10% lidocaine spray will be applied on the cuff of the intubation tube topically and patient will be intubated.

Treatment:

Drug: Lidocaine 10% Spray

steroid group

Active Comparator group

Description:

mometasone furoate spray will be applied on the cuff of the intubation tube topically and patient will be intubated.

Treatment:

Drug: Mometasone nasal spray