A Comparison of Meperidine for Post-Cesarean Analgesia: Bolus Versus Infusion and Bolus

Mercy Research

Status

Completed

Conditions

Cesarean Section

Treatments

Drug: Meperidine

Study type

Interventional

Funder types

Other

Identifiers

NCT01741259

371047-1

Details and patient eligibility

About

The purpose of this study is to determine if epidural meperidine administered by patient-controlled bolus button is equivalent to a low dose infusion plus patient-controlled bolus.

Full description

The objective of this study is to compare the efficacy, patient satisfaction, and incidence of side effects of meperidine patient-controlled epidural analgesia (PCEA) with and without a basal infusion for post-cesarean section analgesia.

Enrollment

273 patients

Sex

Female

Ages

18 to 50 years old

Volunteers

Accepts Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria are as follows:

Over the age of 18
Undergoing non-urgent, non-emergent cesarean section at Mercy Hospital St. Louis

Exclusion Criteria:

non-English speaking
mentally disabled
allergy to meperidine
seizure disorder
renal impairment defined as a serum creatinine >0.8 mg/dL or patients who give a history of renal impairment
fever greater than 101
patients receiving low molecular weight heparin at any dose or unfractionated heparin at doses greater than 5000 u subcutaneous twice daily
pre-eclampsia requiring magnesium due to post-partum room assignment
obstructive sleep apnea due to post-partum room assignment
post-partum hemorrhage due to post-partum room assignment