A Comparison of Propofol Based Total Intravenous Anesthesia and Sevoflurane Based Balanced Anesthesia on Renal Protection During Lung Transplantation Under Extracorporeal Membrane Oxygenation - A Prospective, Randomized Trial

Yonsei University

Status and phase: Completed; Phase 4

Conditions: Patients Undergoing Lung Transplantation Under Extracorporeal Membrane Oxygenation

Treatments: Drug: Administration of anesthesia: Sevoflurane; Drug: Administration of anesthesia: Propofol

Study type: Interventional

Funder types: Other

Identifiers

NCT02009280

4-2013-0648

Details and patient eligibility

About

The aim of this study is to investigate whether propofol based total intravenous anesthesia reduces incidence of acute kidney injury following the lung transplantation under extracorporeal membrane oxygenation

Enrollment: 60 patients

Sex: All

Ages: 20+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Sixty adults undergoing lung transplantation under extracorporeal membrane oxygenation

Exclusion criteria

• Patient having propofol allergy, BMI > 30 kg/m2

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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60 participants in 2 patient groups

Propofol group

Experimental group

Description:

Propofol group

Treatment:

Drug: Administration of anesthesia: Propofol

Sevoflurane group

Active Comparator group

Description:

Sevoflurane group

Treatment:

Drug: Administration of anesthesia: Sevoflurane