A Comparison of the Effects of Krill Oil and Fish Oil Supplementation on Muscle Function in Older Adults

University of Glasgow

Status: Completed

Conditions: Sarcopenia

Treatments: Dietary Supplement: Kril oil; Dietary Supplement: Vegetable oil; Dietary Supplement: Fish oil

Study type: Interventional

Funder types: Other

Identifiers

NCT05869526

FISHKRILL

Details and patient eligibility

About

The aim of the study is to compare the effects of Krill Oil and Fish Oil supplementation on muscle function in older adults. The secondary aim is to investigate the mechanisms underlying the beneficial effects previously observed.

Enrollment: 61 patients

Sex: All

Ages: 60 to 90 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Older adults (aged 60 years or older). BMI less than 30kg/m2

Exclusion criteria

• Participants (diagnosed and being treated for a pre-existing medical condition (cancer, kidney disease, liver disease, diabetes mellitus and cardiovascular disease, uncontrolled hypertension, gait disturbances limiting the ability to perform assessments of muscle function, dementia, affecting muscles known to use drugs (e.g., steroids). History of allergy to fish or fish oil and regular consumption of more than1portion of oily fish per week or use of fish oil or krill oil supplements will also be excluded.

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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61 participants in 3 patient groups, including a placebo group

Fish oil

Active Comparator group

Description:

Fish oil 4 g/day

Treatment:

Dietary Supplement: Fish oil

Krill oil

Active Comparator group

Description:

Krill oil 4g/day

Treatment:

Dietary Supplement: Kril oil

Placebo

Placebo Comparator group

Description:

Vegetable oil 4g/day

Treatment:

Dietary Supplement: Vegetable oil