A Comprehensive Smoking Cessation Intervention Duration Radiation for Upper Aerodigestive Cancers

Johns Hopkins Medicine

Status: Completed

Conditions: Thoracic Neoplasms; Tobacco Use Disorder; Radiation; Head and Neck Neoplasms

Treatments: Other: Comprehensive smoking cessation intervention; Behavioral: Enhanced usual care

Study type: Interventional

Funder types: Other; NIH

Identifiers

NCT02188563

J1407

NA_00089912 (Other Identifier)

P50DE019032 (U.S. NIH Grant/Contract)

Details and patient eligibility

About

Smoking is the greatest risk factor for upper aerodigestive cancers (thoracic or head and neck) and negatively impacts survival and other outcomes, but many patients have difficulty quitting after their diagnosis. Smoking cessation interventions for cancer patients thus far have had limited success. This is a pilot randomized controlled trial designed to determine if a new comprehensive, evidence-based smoking cessation intervention can improve quit rates for cancer patients who smoke.

Enrollment: 30 patients

Sex: All

Ages: 18 to 105 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• New diagnosis of head and neck or thoracic (including lung) cancer
• Undergoing radiation at Johns Hopkins Radiation Oncology for 5 or more weeks
• English-speaking and able to provide informed consent
• Smoked any cigarettes in previous 14 days

Exclusion criteria

• Palliative radiation
• Undergoing stereotactic radiosurgery
• Pregnant or breastfeeding

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

---

30 participants in 2 patient groups

Comprehensive intervention

Experimental group

Description:

New evidence-based comprehensive smoking cessation intervention including several elements that have proven successful in non-cancer patients but not used for cancer patients before.

Treatment:

Other: Comprehensive smoking cessation intervention

Enhanced usual care

Active Comparator group

Description:

Intervention consistent with the U.S. Department of Health and Human Services guidelines for tobacco treatment.

Treatment:

Behavioral: Enhanced usual care