A Cross-Sectional Natural History Study to Evaluate Sweat Volume and Other Phenotypic and Genetic Characteristics in Patients Affected by XLHED

Dermelix Biotherapeutics

Status: Withdrawn

Conditions: XLHED

Study type: Observational

Funder types: Industry

Identifiers

NCT03912792

DMX101-0001

Details and patient eligibility

About

The proposed natural history study will enroll male patients with a diagnosis of XLHED, female carriers of XLHED and healthy volunteers. The study protocol will include collection of XLHED questionnaires and clinical outcomes using minimally invasive technologies. Data will be collected both retrospectively and prospectively.

Clinical outcome assessments will be performed at the NFED Family Conference on July 11-12, 2019. Study participants will be able to complete XLHED questionnaires electronically ahead of the conference.

Sex: All

Ages: Under 80 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Informed Consent
• Males with XLHED, female carriers of XLHED and healthy volunteers

Exclusion criteria

• Treatment with an investigational study drug for XLHED
• Any major medical problems that would prevent her/him from participating in this study
• Known hypersensitivity to pilocarpine or pilocarpine-like muscarinic agonists (Examples: Urecholine, Salagen, Pilocar, and Provocholine)
• Pacemaker

Trial design

0 participants in 2 patient groups

XLHED Patients

Healthy Controls