A Diagnostic Study of the Advanced Endoscopy to Detect Early Esophageal Cancer

King Chulalongkorn Memorial Hospital

Status: Completed

Conditions: Esophageal Neoplasms

Treatments: Device: Olympus; Device: Cellvizio

Study type: Interventional

Funder types: Other

Identifiers

NCT02182804

RP008

Details and patient eligibility

About

This descriptive cross sectional study aims to directly compare the diagnostic capability of the probed-based confocal laser endomicroscopy (pCLE) and the magnifying narrow band imaging (M-NBI) in the Lugol's voiding lesions.

Enrollment: 44 patients

Sex: All

Ages: 20+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age over 20 years
• Having histological-confirmed diagnosis of head and neck cancer
• Having no esophageal symptoms

Exclusion criteria

• Having index cancer of nasopharynx
• History of esophageal surgery
• Having esophageal stricture or obstruction
• Having esophageal varices
• Known case of esophageal cancer
• Uncorrectable coagulopathy and thrombocytopenia
• Pregnancy
• Thyrotoxicosis
• Creatinine clearance less than 30 ml/min
• Allergy to iodine or fluorescein.

Trial design

Primary purpose: Diagnostic

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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44 participants in 1 patient group

Study

Experimental group

Description:

probe-based confocal laser endomicroscopy narrow band imaging with magnification

Treatment:

Device: Cellvizio

Device: Olympus