A Double Blind Randomized Controlled of Placebo and Nebulized Lidocaine for Migraine Headache

Kern Medical Center

Status: Completed

Conditions: Migraine Headache

Treatments: Drug: Lidocaine

Study type: Interventional

Funder types: Other

Identifiers

NCT00287781

#04028

Details and patient eligibility

About

Migraine headaches have previously been shown to be responsive to intranasal lidocaine in a small study. Using a nebulizer to administer the drug would improve the feasibility of using the treatment. It would also spare the patient narcotics with their attendant side effects. Because of the potential for placebo effect a placebo control is necessary in this study.

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Meets IHS criteria for migraine

Exclusion criteria

• Pregnant
• Breast feeding
• Allergic to Lidocaine
• Worst or first Headache
• Abnormal neurological exam
• Substance abuse within 6 months
• Cardiac, liver or pulmonary disease
• Participation n another study within 30 days

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Single Group Assignment

Masking: Double Blind