A Double-blind Randomized Placebo Controlled Clinical Trial Evaluating Effect of Chlorhexidine Gluconate 2% Cloth vs Placebo Cloth Baths on the Incidence of Central Line-Associated Blood Stream Infections in Outpatient Hematopoietic Stem Cell Transplant Patients

The University of Chicago

Status and phase: Completed; Phase 2

Conditions: Stem Cell Transplant Complications

Treatments: Drug: Chlorhexidine Gluconate 2% Wipe; Drug: Placebo Wipe

Study type: Interventional

Funder types: Other

Identifiers

NCT03030989

IRB16-1059

Details and patient eligibility

About

This study evaluates the use of 2% CHG washcloths in an outpatient setting for adults after hematopoietic stem cell transplant in prevention of central line associated blood stream infections. Half of the participants will use 2% CHG washcloths and other half will use placebo washcloths.

Enrollment: 50 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Admitted to the University of Chicago Hematopoietic Stem Cell Transplant Unit for transplant
• Age 18 and up

Exclusion criteria

• Experienced an allergy or rash related to use of chlorhexidine washcloths or other chlorhexidine products
• Extensive open wounds

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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50 participants in 2 patient groups, including a placebo group

Chlorhexidine Gluconate 2% Wipe

Active Comparator group

Treatment:

Drug: Chlorhexidine Gluconate 2% Wipe

Placebo wipe

Placebo Comparator group

Treatment:

Drug: Placebo Wipe