Status and phase
Conditions
Treatments
About
This study is designed to compare the three chemotherapy regimens(TEGAFOX Sequential S-1 or SOX Sequential S-1 or SOX non-Sequential S-1) for postoperative patients with gastric cancer, observe and record the efficacy and tolerance,to evaluate which regimen is better.
Enrollment
Sex
Ages
Volunteers
Inclusion criteria
Exclusion criteria
History of severe hypersensitivity reactions to the ingredients of S-1\TF\5-FU/calcium folinate or oxaliplatin
Inadequate hematopoietic function which is defined as below:
Inadequate hepatic or renal function which is defined as below:
Presence of peripheral neuropathy
Receiving a concomitant treatment with other fluoropyrimidine drug or flucytosine drug
Women who is pregnant or lactating or fertile women of child-bearing potential unless using a reliable and appropriate contraceptive method throughout the treatment period (Including male)
Psychiatric disorder or symptom that makes participation of the patient difficult;
Concomitant illness that might be aggregated by active, non-controlled disease such as congestive heart failure, ischemic heart disease, uncontrolled hypertension or arrhythmia with in six months
Severe complication(s), e.g., paresis of intestines, ileus, radiographically confirmed interstitial pneumonitis or pulmonary fibrosis, glomerulonephritis ,renal failure, poorly-controlled diabetes
Primary purpose
Allocation
Interventional model
Masking
300 participants in 3 patient groups
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Central trial contact
Xiao Chen, MD
Data sourced from clinicaltrials.gov
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