A Follow-up of the Influencing Factors of Dyskinesia in Patients With Parkinson's Disease (PDDIFFU)

Shanghai Jiao Tong University

Status: Unknown

Conditions: Parkinson Disease; Dyskinesias

Study type: Observational

Funder types: Other

Identifiers

NCT04453995

XH-19-014

Details and patient eligibility

About

Parkinson' patients who have not had dyskinesia would be observed for 2 years in a multicenter prospective study with the purposes to clarify the predicting factors of dyskinesia.

Full description

Parkinson' patients with daily levodopa dosage above 200mg and no dyskinesia would be recruited into the study. They would be observed for two years for analyzed the predicting factors of dyskinesia. At the baseline, demographic information, Clinical information, blood sample, picture of tongure coating would be collected at the baseline. All participants were evaluated every three months for two years. The severity of motor symptoms were evaluated every 6 months.

Enrollment: 300 estimated patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• 1. Patients have been clinically diagnosed with Parkinson disease at the recruitment.

2. Patients have received Levodopa treatment with the daily dosage above 200mg.

Exclusion criteria

• 1. be suspicious of atypical Parkinson or other Parkinson syndrome. 2) have experienced dyskinesia. 3) incorporation to the investigation