A Four Month Home Based tDCS Study on Patients With Alzheimer's Disease.

University Hospital of North Norway

Status: Completed

Conditions: Alzheimer Disease

Treatments: Device: transcranial direct current stimulation (tDCS)

Study type: Interventional

Funder types: Other

Identifiers

NCT04759092

TDCS1HB

Details and patient eligibility

About

The study is an open label study on patients with Alzheimer's dementia using home based transcranial direct current (tDCS) stimulation. Aims of the study is to investigate applicability and effect of treatment.

Full description

Active tDCS of 2mA is applied via surface based electrodes daily for 30 minutes over a 4 month period. Anodal electrode is placed over the left temporal lobe. Participants is followed up by home visit and phone calls.

Cognitive tests are performed prior to the treatment period, right after finishing 4 months of treatment and 4 months after treatment is terminated.

Enrollment: 8 patients

Sex: All

Ages: 60 to 85 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age 60-85.
• Fulfil diagnostic criteria of probable Alzheimer's dementia.
• Participants has to live with a caregiver.
• If medicated with cholinesterase inhibitors or memantine, a stable dose the last three months before inclusion is required.

Exclusion criteria

• Implant in head
• Seizure history
• Severe illness,
• Psychosis or depression measured with a cornell score over 11.
• Mini mental status (MMSE) score<17.

Trial design

Primary purpose: Treatment

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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8 participants in 1 patient group

Treatment with tDCS

Experimental group

Description:

Home based treatment with tDCS for four months

Treatment:

Device: transcranial direct current stimulation (tDCS)