A Genetic Study for Alzheimer Dementia: Case-control Study

MinYoung Kim, MD, PhD

Status: Not yet enrolling

Conditions: Alzheimer Dementia (AD)

Study type: Observational

Funder types: Other

Identifiers

NCT06330155

2024-01-032

Details and patient eligibility

About

The purpose of this study is to find out the difference in genetic test results between Alzheimer's dementia patients and healthy subjects.

The investigators want to identify genes that are importantly related to Alzheimer's dementia.

Enrollment: 20 estimated patients

Sex: All

Ages: 60+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion and exclusion criteria

1. Inclusion Criteria: Alzheimer's dementia patient

   • Adult patients over 60 years old
   • Patients with a Alzheimer's dementia patient
   • Total Korean version of mini-mental state examination (K-MMSE) score less than 24
   • Total Clinical Dementia Rating (CDR) over 0.5

2. Inclusion Criteria: healthy subjects

   • Adult healthy over 60 years old
   • Total Korean version of mini-mental state examination (K-MMSE) over 24
   • Total Clinical Dementia Rating (CDR) is 0

3. Exclusion Criteria:

   • Those with severe medical conditions such as unstable conditions of the cardiovascular system, digestive system, respiratory system, endocrine system, etc., who are in poor general condition
   • In the case of a person with impaired consent (MMSE less than 10 points), if not accompanied by a guardian
   • Other cases where the researcher determines that participation in this clinical trial is not appropriate (Patients who are participating in other studies or have participated in other studies within the past 30 days can also participate in this study.)

Trial design

20 participants in 1 patient group

Alzheimer's dementia patient and healthy subjects