A Longitudinal Study of Movement and Participation in Patients With Cerebral Palsy

Chang Gung Medical Foundation

Status

Completed

Conditions

Cerebral Palsy

Study type

Observational

Funder types

Other

Identifiers

NCT01903603

100-4545A3

NSC101-2314-B-182-004-MY3 (Other Identifier)

Details and patient eligibility

About

The primary goal of this study is to establish and evaluate an image-based biomarker for the impaired motor control and sensory information processing present in Cerebral palsy (CP) patients

Full description

Cerebral palsy (CP) may lead to various motor deficits, which further influence the activities and participation. It would be ideal to characterize neural network and motor control model in patients with CP that underlies their clinical behavior by identifying altered neural network and motor control associated with behavioral improvement. The aim of this study is to investigate the brain image and motor control in patients with CP evaluated by multimodal imaging studies utilizing multi-modal techniques and kinematic analysis.

This study includes a prospective longitudinal study of patients with CP over one-year. This study will be executed in 3 phases within 3 years: 1st phase (1st years): to establish the multimodal brain images and motor control, and clinical outcomes protocol with a prospective one-year follow-up study in healthy subjects; 2nd phase (2nd years): to establish the brain images and motor control, and clinical outcomes with a prospective one-year follow-up study in older patients with CP; and 3rd phase (3rd years): to establish the brain images and motor control, and clinical outcomes with a prospective one-year follow-up study in younger patients with CP. In a prospective longitudinal study, each participant received 3-times measurements: at the beginning, 6 months later, and one year after the first data collection point

Enrollment

80 patients

Sex

All

Ages

4 to 20 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria