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A Longitudinal Study of Multimodal Resonance Imaging in Stroke Patients

S

Southeast University

Status

Unknown

Conditions

Stroke

Study type

Observational

Funder types

Other

Identifiers

NCT02024503
2013CB733803

Details and patient eligibility

About

Imaging of the ischaemic penumbra with a particular diffusion-weighted imaging (DWI)/ perfusion-weighted imaging (PWI) mismatch is a promising approach to the selection of patients with acute ischaemic stroke for trials of intervention. The investigators want to apply multimodal resonance imaging methods such as functional magnetic resonance imaging ( fMRI), diffusion tensor imaging (DTI), arterial spin labeling (ASL) to guide treatment and predict the prognosis of stroke.

Enrollment

800 estimated patients

Sex

All

Ages

40 to 85 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

Time from the onset of stroke till hospital within 24 hours. With clinical characteristics such as hemiplegia, headache. Willing and able to comply with the study procedures and provide written informed consent to participate in the study.

Patients must understand the nature of the study and give informed consent.

Exclusion criteria

The onset of stroke out of 24 hours. Pregnant women. Patients with intracranial metallic bodies from prior neurosurgical procedure, implanted pacemaker, medication pump, vagal stimulator, deep brain stimulator, TENS unit or ventriculoperitoneal shunt.

Past history of seizures within one year or unexplained loss of consciousness. Family history of epilepsy.

Trial design

800 participants in 2 patient groups

Experimental group
Description:
Hospitalized patients with acute stroke.
Control group
Description:
Healthy Volunteers.

Trial contacts and locations

1

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Central trial contact

Cheng-yu Peng

Data sourced from clinicaltrials.gov

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