A Low Glycemic Load Diet During Pregnancy in Overweight Women

Boston Children's Hospital

Status: Completed

Conditions: Overweight; Pregnancy

Treatments: Behavioral: Low fat diet; Behavioral: Low glycemic load

Study type: Interventional

Funder types: Other; NIH

Identifiers

NCT00364403

R03DK073335 (U.S. NIH Grant/Contract)

Details and patient eligibility

About

This study will compare the effects of a low glycemic load versus standard diet for pregnancy on outcomes related to risk for obesity, diabetes, and heart disease in both mother and infant.

Enrollment: 60 estimated patients

Sex: Female

Ages: 25+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Pregnant women with prepregnant or first trimester BMI equal to or greater than 25 kg/m2 and less than 45 kg/m2
• Singleton pregnancy
• Willing to consume the diets for duration of pregnancy
• Participant to be at week 28 or less of pregnancy at baseline visit

Exclusion criteria

• Smoking during pregnancy
• Major medical illness (e.g., diabetes mellitus, hypertension, thyroid disease)
• Patients taking prescription medication known to affect body weight
• Alcohol consumption during pregnancy
• Patients who declare their intention to deliver infants in the environment outside of Beth Israel Deaconess Medical Center, Boston
• High level of physical activity

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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60 participants in 2 patient groups

1

Experimental group

Description:

Low glycemic load diet

Treatment:

Behavioral: Low glycemic load

2

Active Comparator group

Description:

Low fat diet

Treatment:

Behavioral: Low fat diet