A Low-residue Diet vs Clear Liquid Diet as a Bowel Colonoscopy Preparation With Polyethylene Glycol (PEG)

Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran

Status: Completed

Conditions: Colonoscopy

Treatments: Dietary Supplement: Clear Liquid Diet; Dietary Supplement: Low-residue Diet

Study type: Interventional

Funder types: Other

Identifiers

NCT03358537

001157

Details and patient eligibility

About

This was a randomized, endoscopists' blinded comparison of bowel colonoscopy cleansing and tolerability of a prespecified low-residue diet compared with a clear liquid diet and Polyethylene Glycol bowel preparation. Outcome measures included efficacy of bowel preparation, patient preparation tolerability and side-effects.

Full description

An adequate examination is dependent on the bowel colonoscopy cleansing of stool. There are many different colon preparations, however endoscopists traditionally recommend the patient remain on a clear liquid diet for at least 24 h prior to their colonoscopy to reduce continued residue inflow into the colon from the small bowel, in addition the large volume preparation with PEG. The most common problems leading to less than adequate colon cleansing include lack of compliance with the clear liquid diet and difficulty taking the large volume preparation.

Enrollment: 215 patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Out-patient scheduled for colonoscopy

Exclusion criteria

• Subjects under 18 years of age
• Pregnancy
• Subjects with decompensated metabolic, renal, cardiac and psychiatric disease
• Allergy to PEG
• Refuse participation

Trial design

Primary purpose: Other

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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215 participants in 2 patient groups

Clear Liquid Diet

Active Comparator group

Description:

110 subjects received clear liquid diet 24 hours before colonoscopy

Treatment:

Dietary Supplement: Clear Liquid Diet

Low-residue Diet

Active Comparator group

Description:

105 subjects received a prespecified low-residue diet 24 hours before colonoscopy

Treatment:

Dietary Supplement: Low-residue Diet