A Magnetic Resonance Imaging Study of Patients With Cervical Spondylosis (Tractocervical)

Assistance Publique - Hôpitaux de Paris

Status: Completed

Conditions: Cervical Spondylosis

Treatments: Device: DTI - Diffusor Tensor Imaging

Study type: Interventional

Funder types: Other

Identifiers

NCT01243684

P090404

Details and patient eligibility

About

This study aims at evaluating spinal cord structure using diffusion tensor imaging in patients with cervical spondylosis.

Full description

Diffusion tensor imaging (DTI) of the cervical spinal cord will be performed in patients with cervical spondylosis with varying degrees of symptoms and in healthy control subjects. Fibre tracking of main spinal tracts will be performed. Regions of interest will also be identified. Diffusion parameters will be extracted. This will allow quantification of degree of damage in of the spinal cord. The findings will be related to motor function measures and comprehensive clinical tests of sensory and motor function.

Enrollment: 40 patients

Sex: All

Ages: 18 to 70 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• 18-70 years old
• Sufficiently cooperative
• Cognitively understands study and implications
• Signed informed consent
• Symptomatic cervical spondylosis

Exclusion criteria

• MRI contraindications (e.g., pacemaker, metal implants, claustrophobia)
• Previous pathology that would impact behavioural measures
• Anxiety and poor cooperation
• Previous neurological condition
• Pregnancy

Trial design

Primary purpose: Diagnostic

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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40 participants in 2 patient groups

Healty volunteers

Active Comparator group

Treatment:

Device: DTI - Diffusor Tensor Imaging

Patients

Experimental group

Treatment:

Device: DTI - Diffusor Tensor Imaging