A Methadone Maintenance Treatment Outcome Study in Three Provinces in China

Centers for Disease Control and Prevention (CDC)

Status: Completed

Conditions: Herpes Simplex Type II; Syphilis; Hepatitis C; HIV

Treatments: Behavioral: MMT provider dosage training; Behavioral: targeted counseling; Other: national guidelines

Study type: Interventional

Funder types: Other; Other U.S. Federal agency

Identifiers

NCT01315054

CN_09_217 (Other Grant/Funding Number)

CDC-CGH-6014

Details and patient eligibility

About

The primary goal of this PHE is to determine the effectiveness of a tailored education program for MMT service providers. It was to be evaluated through methadone dose levels prescribed to new patients after training completion. The effects of methadone dose, with and without the inclusion of additional counseling services, would be measured through MMT retention and illicit opioid use.

Full description

Methadone treatment has became one of main actions taken in China to control the spread of HIV among drug users. However，the average methadone dose used is relatively low. An intensive methadone maintenance treatment (MMT) provider training on methadone dosage may be effective in increasing the methadone dose levels prescribed to new patients. The study will evaluate the effectiveness of a tailored education program for MMT service providers using subsequent methadone dose prescribed to new patients. The effects of methadone dose, with and without the inclusion of additional psychosocial services, will then be measured through MMT retention and illicit opioid use.

Enrollment: 4,258 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria:

• client participants will include both men and women who are opiate-dependent drug users who started MMT not more than one month prior to enrollment in the study
• 18 years of age or older
• residing in the study areas

Trial design

Primary purpose: Health Services Research

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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4,258 participants in 3 patient groups

Control arm

Other group

Description:

Using currently practiced methadone dosage prescription methods

Treatment:

Other: national guidelines

MMT provider dosage training

Experimental group

Description:

Intensive health care provider training on prescribing methadone dosage based on national guidelines

Treatment:

Other: national guidelines

Behavioral: MMT provider dosage training

MMT provider dosage training/counseling

Experimental group

Description:

Intensive health care provider training on prescribing methadone dosage, plus providing on-site psychosocial counseling services and peer support to clients .

Treatment:

Other: national guidelines

Behavioral: targeted counseling

Behavioral: MMT provider dosage training