A Method to Optimize Mecanical In-exsufflation in Neuromuscular Diseases (COUGHELP)

Centre d'Investigation Clinique et Technologique 805

Status: Completed

Conditions: Neuromuscular Disease

Treatments: Device: Cough Assist® (JH Emerson Compagny, Cambridge, MA, USA)

Study type: Interventional

Funder types: Other

Identifiers

NCT02137304

2013-A01771-44

Details and patient eligibility

About

The investigators want to demonstrate that there is an optimal expiratory pressure when using mecanical in-exsufflation for each patient in neuromuscular disease. This compromise is between the need to generate a high pressure difference between alveoli and the mouth and the need to avoide and superior airways collapsus.

Full description

he investigators want to demonstrate that there is an optimal expiratory pressure when using mecanical in-exsufflation for each patient in neuromuscular disease. This compromise is between the need to generate a high pressure difference between alveoli and the mouth and the need to avoide and superior airways collapsus.

Enrollment: 40 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• man or female age18 years
• neuromuscular disease
• coughassist adaptation treatment
• peak cough flow<270liter/minute

Exclusion criteria

• acute organ failure
• insufflation contrindication
• pregnant women/no affiliation to a social security scheme
• plan of legal protection

Trial design

Primary purpose: Treatment

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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40 participants in 1 patient group

neuromuscular patients

Experimental group

Description:

Cough Assist® (JH Emerson Compagny, Cambridge, MA, USA)

Treatment:

Device: Cough Assist® (JH Emerson Compagny, Cambridge, MA, USA)