A Multi-center Clinical Longitudinal Study of Neuropathic Pain by Collecting Data

Shanghai Jiao Tong University

Status: Enrolling

Conditions: Pain

Treatments: Device: A multi-center clinical longitudinal study of neuropathic pain by collecting data on patients' brain physiology and cognitive function

Study type: Observational

Funder types: Other

Identifiers

NCT06290024

XH-23-013

Details and patient eligibility

About

A multi-center clinical longitudinal study of neuropathic pain by collecting data on patients' brain physiology and cognitive function

Full description

Using the use of pain visual analog scale (VAS), digital pain grading method (NRS), neuropathic pain assessment scale (DN4), sleep quality (Pittsburgh sleep quality index, Ascens insomnia scale), social support assessment scale (SSQ), Montreal cognitive assessment scale (MoCA), Barrett impulse scale (BIS), anxiety and depression score (GAD-7, PHQ-9), emotional tasks, cognitive function (N-back, time perception, delay-discount), electroencephalogram (EEG), near-infrared brain function imaging (fNIRS) and other indicators to study the dynamic changes of various factors in the process of acute pain.

Enrollment: 2,000 estimated patients

Sex: All

Ages: 18 to 85 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. The subjects voluntarily participated in the study and signed an informed consent form;
2. The age is between 18 years old (inclusive) and 85 years old (inclusive), regardless of gender;
3. Body mass index (BMI) ≤ 45;
4. Clinically clearly diagnosed neuropathological pain (pain VAS score ≥4 or above);
5. Did not participate in the drug/medical device test within 3 months before the test;

Exclusion criteria

Trial design

2,000 participants in 1 patient group

Patients with neuropathic pain

Description:

With prospective and longitudinal research design, patients with neuropathic pain that meet the entry/displacement standards will be included in the group and receive the routine diagnosis and treatment of the pain department. At the same time, the patients admitted to the group will be clinical observation and studied. After the diagnosis and treatment, follow-up will be carried out until 3 months after joining the group.

Treatment:

Device: A multi-center clinical longitudinal study of neuropathic pain by collecting data on patients' brain physiology and cognitive function