A Multi-center Study to Determine the Prevalence and Influence of Pertussis on Subacute Cough in Shenzhen

Southern University of Science and Technology

Status

Unknown

Conditions

Pertussis

Chronic Cough

Treatments

Procedure: Blood sample

Procedure: Throat swab

Procedure: Data collection

Study type

Observational

Funder types

Other

Identifiers

NCT04694963

WLW-SC-Pertussis

Details and patient eligibility

About

A prospective, multi-center, observational clinical trail. Aim to evaluate the real incidence of COPD pertussis and the impact of pertussis on subaute cough.

Full description

Investigate the incidence and epidemiological characteristics of pertussis infection in subaute cough population.
To explore the relationship between pertussis infection and subaute cough.

Enrollment

500 estimated patients

Sex

All

Ages

40 to 80 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

The cough lasts 3 to 8 weeks and there is no obvious evidence of lung disease on chest X-ray.

Exclusion criteria

1. Major diseases except subaute cough; 2. Significant abnormality in laboratory examination; 3. Clinical diagnosis of lung cancer, bronchiectasis, pneumoconiosis or other simple restrictive ventilation dysfunction; 4. Patients with a history of asthma, allergic rhinitis, or a blood eosinophil count of 2600/mm3 (0.6x10^9/L) within 4 weeks; 5. Currently suffering from active tuberculosis; 6. Patients with life-threatening pulmonary embolism, or al-antitrypsin deficiency, or cystic fibrosis; 7. Patients who have undergone lung resection.