A Multicenter Clinical Study of Echocardiographic Assessment of Right Heart Function and Implications of Prognosis in Diabetes

Xie Mingxing

Status: Not yet enrolling

Conditions: Diabetes; Prognosis

Study type: Observational

Funder types: Other

Identifiers

NCT04964713

2021 V1.0

Details and patient eligibility

About

The aims of this study are to 1. Evaluate the right heart structure and function in T2DM and Prediabetes patients by speckle tracking echocardiography, and to further investigate the influence of left heart on right heart structure and function in T2DM and Prediabetes patients. 2. To explore the prognostic value of right ventricular function in T2DM patients.

Full description

This study will recruit 1000 T2DM patients and 500 Prediabetes and 500 healthy controls. Assessing the left heart and right heart structure and function by speckle tracking echocardiography. Patients with T2DM were followed up for adverse cardiovascular outcome events (myocardial infarction, cerebrovascular stroke, or cardiovascular death, hospitalization for heart failure). And the study aimed to 1. 1. Evaluate the right heart structure and function in T2DM and Prediabetes patients by speckle tracking echocardiography, and to further investigate the influence of left heart on right heart structure and function in T2DM and Prediabetes patients. 2. To explore the prognostic value of right ventricular function in T2DM patients.

Enrollment: 2,300 estimated patients

Sex: All

Ages: 35 to 79 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

people with T2DM according to the WHO 2006 criteria

Exclusion criteria

including history or symptoms of CAD valvular heart disease, rhythm disturbances cardiomyopathy congenital heart disease symptomatic heart failure pulmonary disease

Trial design

2,300 participants in 3 patient groups

type 2 diabetes

Description:

T2DM was defined according to the WHO 2006 criteria. Assessing the left heart and right heart structure and function of T2DM by speckle tracking echocardiography.

Prediabetes

Description:

According to the WHO 2006 criteria, combining impaired fasting glucose and impaired glucose tolerance as prediabetes. Assessing the left heart and right heart structure and function of prediabetes by speckle tracking echocardiography.

normal glucose metabolism(NGM)

Description:

Assessing the left heart and right heart structure and function of NGM by speckle tracking echocardiography.