A Network & Dyad HIV Prevention Intervention for IDU's - 1

Johns Hopkins Bloomberg School of Public Health

Status and phase: Completed; Phase 2

Conditions: Hepatitis; HIV

Treatments: Behavioral: Control Condition; Behavioral: Intervention Condition

Study type: Interventional

Funder types: Other; NIH

Identifiers

NCT00218335

1R01DA016555-01 (U.S. NIH Grant/Contract)

5R01DA016555-02 (U.S. NIH Grant/Contract)

R01-16555-1

3R01DA016555-02S1 (U.S. NIH Grant/Contract)

3R01DA016555-03S1 (U.S. NIH Grant/Contract)

5R01DA016555-04 (U.S. NIH Grant/Contract)

3R01DA016555-01S1 (U.S. NIH Grant/Contract)

DESPR DA016555-1

NIDA-16555-1

5R01DA016555-03 (U.S. NIH Grant/Contract)

5R01DA016555-05 (U.S. NIH Grant/Contract)

Details and patient eligibility

About

The purpose of this study is to evaluate a peer-based HIV prevention intervention that targets active injection drug users and their drug and sex partners.

Full description

HIV seroincidence among injection drug users remains high, with unprotected sexual contact substantially contributing to new HIV infections among injection drug users (IDUs). Interventions that are culturally competent and target drug users' main sex and drug partners may be especially effective for HIV/STI and HCV control and prevention.

The intervention to be tested in this study draws upon theoretical and empirical evidence suggesting that peer educator programs can have significant effects on the risk-related behaviors of both the educators and the peers whom they educate. Specifically, through group and individual focused sessions, participants learn and practice skills designed to reduce drug and sex related risk behaviors. Furthermore, individuals and their main risk partners attend a training session that focuses on risk reduction within their relationship.

Enrollment: 1,024 patients

Sex: All

Ages: 18 to 75 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

(i)Self reported injection drug use within the prior 6 months; (ii)Willingness to invite a risk network member into the study and to talk about HIV prevention; (iii)Age 18 or older

Exclusion criteria

• Not concurrently enrolled in another HIV prevention intervention

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

---

1,024 participants in 2 patient groups

Intervention Condition

Experimental group

Description:

Participants were trained to be Health Educators. The intervention focused on HIV risk reduction by teaching knowledge and skills to reduce injection, drug splitting, and sex risk, and by teaching communication skills to conduct outreach to personal risk network members. The intervention consisted of five group-based sessions, one individual session, and one dyad session with a risk network member.

Treatment:

Behavioral: Intervention Condition

Control Condition

Active Comparator group

Description:

The control condition focused on injection drug-use related topics (e.g. HIV testing, Hepatitis C and drug overdose). The sessions were educational and did not include skills training. The control condition consisted of five group-based sessions.

Treatment:

Behavioral: Control Condition