A New Anatomical Classification of Portal Vein Location of Pancreas Tumors

Sisli Hamidiye Etfal Training and Research Hospital

Status: Completed

Conditions: Pancreatic Neoplasm Malignant Head Primary

Treatments: Procedure: graft reconstruction; Procedure: primary repair; Procedure: segmental resection

Study type: Interventional

Funder types: Other

Identifiers

NCT04416685

PVR-2019

Details and patient eligibility

About

In this retrospective study, we recorded the location of pancreatic tumors and relation/proximity to the portal vein. The surgical difficulty and requirement of additional interventions were also evaluated.

Full description

Between May 2014 and October 2018, all patients who underwent PD procedure were retrospectively reviewed. This retrospective cohort study identified all consecutive patients with T3 (stage IIA to III) adenocarcinoma of the head of the pancreas, who underwent concomitant venous (PV/SMV) resection. Those patients with locally advanced tumors that were not responded to neoadjuvant therapy were excluded. The local ethical committee was approved this study.

Data collection included demographical features, tumor characteristics including the PV level of the tumor considering computed tomography results, neoadjuvant therapy, surgical data, hospital stay, morbidity and mortality.

Anatomical classification was established based on the relationship between portal confluence (PC) and tumor location (Figure I). Those tumors located superior to the PC were classified as Level I, whereas tumors on the confluence inferiorly located to PC were classified as Level II and Level III.

Enrollment: 43 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• This retrospective cohort study identified all consecutive patients with T3 (stage IIA to III) adenocarcinoma of the head of the pancreas, who underwent concomitant venous (PV/SMV) resection.

Exclusion criteria

• Those patients with locally advanced tumors that were not responded to neoadjuvant therapy were excluded.

Trial design

Primary purpose: Treatment

Allocation: Non-Randomized

Interventional model: Single Group Assignment

Masking: None (Open label)

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43 participants in 3 patient groups

Level 1

Other group

Description:

Those tumors located superior to the portal confluence were classified as Level I,

Treatment:

Procedure: segmental resection

Procedure: primary repair

Level II

Other group

Description:

those tumors located on the confluence (involving the confluence) located on the portal confluence

Treatment:

Procedure: segmental resection

Procedure: primary repair

Level III

Other group

Description:

those tumors located inferior to the portal confluence

Treatment:

Procedure: segmental resection

Procedure: graft reconstruction