A New Deep-learning Based Artificial Intelligence Iterative Reconstruction (AIIR) Algorithm in Low-dose Liver CT

Qianfoshan Hospital

Status: Not yet enrolling

Conditions: Deep Learning

Treatments: Other: low-dose CT

Study type: Interventional

Funder types: Other

Identifiers

NCT05550012

LD-SH-2022

Details and patient eligibility

About

CT-enhanced scans are routine imaging modality for the diagnosis and follow-up of liver disease. However, this means that patients will receive more radiation dose. Therefore, it is necessary to reduce the radiation dose received by patients as much as possible. Deep learning-based reconstruction algorithms have been introduced to improve image quality recently. For many years, researchers attempt to maintain image quality using an advanced method while reducing radiation dose. Recently, a new deep-learning based iterative reconstruction algorithm, namely artificial intelligence iterative reconstruction (AIIR, United Imaging Healthcare, Shanghai, China) has been introduced. In this study, we evaluate the image and diagnostic qualities of AIIR for low-dose portal vein and delayed phase liver CT with those of a KARL method normally used in standard-dose CT.

Full description

In our hospital, patients with abdominal pelvic cancer undergo follow-up low-dose CT for the evaluation of treatment plan after clinical treatment or disease progress. The raw-data of low-dose CT were collected retrospectively and reconstructed using KARL and AIIR algorithm. In this study, we evaluate the image and diagnostic qualities of AIIR for low-dose portal vein and delayed phase liver CT with those of a KARL method normally used in standard-dose CT.

Enrollment: 100 estimated patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• those scheduled for contrast-enhanced liver CT

Exclusion criteria

• images affected by artifacts (motion or implants)

Trial design

Primary purpose: Other

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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100 participants in 2 patient groups

standard-dose CT

No Intervention group

Description:

those patients undergo standard-dose liver CT in portal vein and delayed phase

low-dose CT

Experimental group

Description:

those patients undergo low-dose liver CT in portal vein and delayed phase

Treatment:

Other: low-dose CT