A New Paradigm for Illness Monitoring and Relapse Prevention in Schizophrenia

Dartmouth Health

Status: Completed

Conditions: Schizophrenia; Schizoaffective Disorder

Treatments: Behavioral: Treatment as usual; Behavioral: Device: Smartphone

Study type: Interventional

Funder types: Other

Identifiers

NCT01952041

MH103148-01 D14022

Details and patient eligibility

About

This study was a 2-arm randomized control trial (RCT) designed to test a multi-modal smartphone data collection system that provided mobile monitoring of schizophrenia to detect early signs of relapse. The RCT compared an arm with participants who received treatment as usual with an arm that received the smartphone system for a year.

Enrollment: 149 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Diagnostic and Statistical Manual of Mental Disorders IV (DSM-IV) criteria for schizophrenia, schizoaffective disorder, or psychosis not otherwise specified based on a chart diagnosis
• 18 years or older
• An inpatient psychiatric hospitalization, daytime psychiatric hospitalization, outpatient crisis management, or short-term psychiatric hospital emergency room within 12 months before study entry
• Willing and able to provide informed consent

Exclusion criteria

• Hearing, vision, or motor impairment that make it impossible to operate a smartphone (determined using a demonstration smartphone for screening)
• 6th grade reading level (determined by Wide Range Achievement Test- 4th Edition)

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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149 participants in 2 patient groups

Device: Smartphone

Experimental group

Description:

Participants in the smartphone intervention arm received treatment as usual in addition to receiving a smartphone with the study application. The study application identified relapse risk and prompted the clinical team to provide enhanced services.

Treatment:

Behavioral: Device: Smartphone

Treatment as Usual

Active Comparator group

Description:

Treatment as usual included outpatient case management, linkage to services and medication monitoring.

Treatment:

Behavioral: Treatment as usual