A New Prognostic Scoring System for Spontaneous Ruptured Hepatocellular

Huazhong University of Science and Technology

Status: Completed

Conditions: Rupture, Spontaneous

Treatments: Procedure: Liver resection

Study type: Observational

Funder types: Other

Identifiers

NCT03504358

Zhupeng002

Details and patient eligibility

About

Develop a new scoring system for HCC patients with tumor rupture.

Full description

There has been no special prognostic scoring system for HCC patients with tumor rupture in the literature. In this work, we obtained all survival risk factors of ruptured HCC patients who underwent partial hepatectomy using multivariable Cox regression analysis. Furthermore, we develop and validate a new postoperative scoring system for patients with spontaneous HCC rupture based on the these results.

Enrollment: 129 patients

Sex: All

Ages: 15 to 75 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Received partial hepatectomy; with Child A or B liver function.

Exclusion criteria

• Without complete data；loss of follow-up; had reveived repeated transcatheter arterial chemoembolization before rupture; received non-radical resection.

Trial design

129 participants in 3 patient groups

Analysis before liver resection

Description:

Multivariate analysis of predictive factors associated with survival

Treatment:

Procedure: Liver resection

Different risk group

Description:

Low-risk group, moderate-risk group, high-risk group

Treatment:

Procedure: Liver resection

Model comparison

Description:

Comparison of models in predicting survival

Treatment:

Procedure: Liver resection