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A New Surgical Strategy to Protect the Inferior Parathyroid

Zhejiang University logo

Zhejiang University

Status

Not yet enrolling

Conditions

Thyroid Cancer

Treatments

Procedure: Resection based on "thymus-vascular-inferior parathyroid" complex

Study type

Interventional

Funder types

Other

Identifiers

NCT05758025
2022-0077

Details and patient eligibility

About

The incidence of temporary hypoparathyroidism after thyroid surgery is 14%-60%, and the incidence of permanent hypoparathyroidism is 4%-11%. The protection of parathyroids has always been the focus and difficulty of thyroid surgery. The anatomical position of the superior parathyroids is relatively fixed, and can be preserved in situ easily; while the anatomical position of inferior parathyroids varies greatly between patients. It is always difficult to look for, identify, and protect them. Concepts such as thyro-thymic ligament and "thymus-vascular-inferior parathyroid plane" were raised to help identify the inferior parathyroids. We found that this surgical strategy can protect inferior parathyroids in situ effectively in our retrospective studies. Thus, we are going to carry out a prospective study to compare the new method and the traditional method of thyroidectomy, to see if more inferior parathyroids can be protected in situ through the new surgical strategy.

Enrollment

506 estimated patients

Sex

All

Ages

18 to 70 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • initial thyroid surgery; thyroidectomy with/without central lymph node dissection

Exclusion criteria

  • coexisting parathyroid disease; need lateral neck dissection; history of radio-iodine ablation treatment

Trial design

Primary purpose

Treatment

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

Quadruple Blind

506 participants in 2 patient groups

Resection based on "thymus-vascular-inferior parathyroid" complex
Experimental group
Treatment:
Procedure: Resection based on "thymus-vascular-inferior parathyroid" complex
Traditional thyroidectomy method
No Intervention group

Trial contacts and locations

1

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Central trial contact

Qunzi Zhao, M.D.

Data sourced from clinicaltrials.gov

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